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The action series Zone of the Enders may have a sequel on the way, judging by the pictures shown during the event itself by Hideo Kojima.
The project is still experimental, with Kojima still testing the feasibility of using Fox Engine engine for the production of the game.
The creator of Metal Gear is however confident about this project, the point would have revealed that a sequel to Zone of the Enders: The 2nd Runner, the title originally released on the PlayStation 2 in 2003.
This information indicates that the first events of the game will go on ancient civilization, stay with the images available via Twitter by several participants at the event (via NeoGAF).